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Medical professionals likely spend a great deal of time trying to determine the best treatment options for their patients while applying the principles of evidence-based practice (EBP). UpToDate offers the most reliable, evidence-based clinical information available. It is the resource that helps more than 2 million medical professionals worldwide make more informed evidence-based healthcare decisions.


Multiple studies have demonstrated UpToDate is the only clinical decision support resource associated with improved quality, shorter lengths of stay, and lower mortality rates.1 With an ever-increasing focus on improving patient care using evidence-based programs, medical professionals turn to UpToDate for clinical decision support.

Additional UpToDate benefits:

  • Stay current with comprehensive coverage of more than 12,300 clinical topics and 37,000 graphics in over 25 specialties to find the answers to your clinical questions.

  • View "What's New" and "Practice Changing UpDates" which provides you with thoroughly researched recommendations and updates that may change usual clinical practice, as well as summaries of new developments organized by specialty.

  • Research select drug monographs that provide content on medication dosing, side effects, and interactions through our drug reference, Lexicomp®, available all in one resource.

  • Access reliable content when and where you need it with hands-free  search within our mobile app to get you the answers quickly and easily.*

  • Explore more than 750 disease-specific society guideline link topics, each providing direct links to multiple society and government-sponsored guidelines from around the world. 

Trust the quality of information in UpToDate

With our comprehensive editorial process and input from physician leaders, we review and interpret the best available information for you and make actionable recommendations, including topics that reflect evidence-based critical care. UpToDate provides a discussion of the basis for these recommendations, allowing you to best integrate these with your own clinical judgment and find the best evidence-based treatment for your patient.


Subscribe to UpToDate and see for yourself how evidence-based management can help you provide optimal patient care. We offer several payment methods for your convenience.

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What is evidence-based medicine?

A systematic and transparent editorial policy for identifying, reviewing, and synthesizing clinical evidence as it applies to a clinical question.

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