Clinical Knowledge Question Results

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Question: Which of the following is NOT routinely recommended to decrease the risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis?

24% of
Medical Professionals
Chose A


5% of
Medical Professionals
Chose B


37% of
Medical Professionals
Chose C

35% of
Medical Professionals
Chose D

Answer: C. A randomized trial of atorvastatin for prevention of CVD in patients with RA was stopped early because of lower than expected number of events, but did not show a statistically significant decrease in CV events. We use the same guidelines for initiating statin therapy in a patient with RA as in the general population. Usual measures to modify CV risk and minimizing duration of glucocorticoid therapy can decrease risk in RA. Observational data also suggest that strict control of inflammation in RA with use of therapy to decrease synovial inflammation may reduce the development of progression of cardiovascular disease.

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