See why over 30,000 institutions
around the world trust UpToDate.

UpToDate is the only clinical decision support resource
associated with improved outcomes.

Smarter Decisions. Better Care.

UpToDate® is the premier evidence-based clinical decision support resource.

UpToDate provides clinicians with:

  • Graded recommendations for care: Current and reliable medical information based on the best available evidence. We use the GRADE system, developed by Dr. Gordon Guyatt at McMaster University, so clinicians can quickly assess the strength of the recommendation and the quality of evidence supporting it.
  • Comprehensive clinical content: UpToDate content covers 22 specialties of medicine – more than 10,500 clinical topics can help clinciians treat a wide array of ailments quickly and confidently.
  • Award-winning mobile apps: Current, evidence-based recommendations for care are now available anytime, anywhere on mobile devices.
  • Drug information and interactions database: UpToDate partners with Lexicomp® to provide information on more than 5,400 unique drugs. 
  • Medical calculators: UpToDate contains over 160 calculators

UpToDate topics are viewed more than 23 million times per month

Offering comprehensive coverage of more than 10,500 clinical topics

Unlimited access to more than 28,000 easy-to-search graphics

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What's New?

Read What’s New in each specialty, including Practice Changing UpDates that have an immediate impact on clinical decisions.

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Sample Topics


UpToDate uses the GRADE system developed by Dr. Gordon Guyatt at McMaster University.

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Sample Topics


More than 60 studies confirm that widespread use of UpToDate is associated with improved patient care.

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"It is now hard to remember what the practice of medicine was like before UpToDate. With my smart phone, laptop, or desktop computer, I use it nearly every day to provide the best possible care for my patients."

David Cornish, MD

"I use UpToDate daily while seeing patients; it has saved me (and them) numerous diagnostic and therapeutic misadventures."

Edwin Scott, MD

"I go back to UpToDate for every single patient to make sure what we recommended is really state-of-the-art. It is often rewarding to read precise updates of what might influence my therapy decisions in cases that are never just routine."

Rainer Arendt, MD
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